Unlike MDI - where variation of insulin absorption can be high – Continuous subcutaneous insulin infusion has a much lower variation of absorption¹. CSII therapy allows the setting of different basal rates - to best match the patient’s metabolic requirements. This provides a more physiological delivery of insulin and allows the patient to react, based on BG readings, to adjust the insulin levels across the day - for better control.

SAP gives the patient clear data updates allowing him to see how food, insulin, exercise and other daily activities affect his blood glucose level – potentially improving overall glucose management. A sensor-augmented pump (SAP) combines the use of an insulin pump with a continuous glucose sensor (CGM technology) that transmits glucose readings to the pump. Use of CGM allows the patients to continuously, monitor their glucose level and take a more informed decision on blousing, meaning further improved HbA1C level and reduced time spent in hypoglycaemia^2,3.

CSII therapy is flexible, allowing the setting of different hourly basal rates which will offer the patient a more physiological method of insulin delivery to meet her metabolic demands. Adjusting the overnight insulin infusion rates can compensate for the ‘Dawn phenomenon’ and reduce fasting blood glucose level.

SAP Therapy provides clear data updates, combining the use of an insulin pump with a continuous glucose sensor (CGM technology) that transmits glucose readings to the pump every 5 min. Plus, SAP goes further by enabling this patient to be alerted when the glucose is reaching the defined high threshold - avoiding her morning hyperglycaemia.

With CSII, temporary basal rates can be initiated pre-exercise, to ensure circulating insulin levels match needs experienced during increased activity. To avoid hypoglycaemia, they can be extended beyond the exercise period, as low blood glucose level events can often occur hours after exercise.

In addition, basal rate can also be suspended when signs or symptoms of hypoglycaemia are noticed by the patient.

SAP Therapy provides clear data updates, combining the use of an insulin pump with a continuous glucose sensor (CGM technology) that transmits glucose readings to the pump. Use of CGM provides the additional advantage of uncovering glucose excursions and reducing hypoglycaemia during the day and night^3,12,13 but also during and after the exercise - which is a particular challenge for this patient.

SAP therapy provides the opportunity for this patient to adjust the insulin level according to food and exercise with the goal of improving overall glucose management and improving his patient quality of life.

CSII therapy enables the setting of different basal patterns, to work in harmony with the patient's changing lifestyle. For example:

• Set her a standard basal pattern for her week days when she’s traveling more
• Set a second basal pattern for her weekends

The basal patterns can be easily changed to the new time zone by setting the clock on the pump.

SAP therapy will provide the patient with clear data updates, combining the use of an insulin pump with a continuous glucose sensor (CGM technology) that transmits glucose readings to the pump.

Use of CGM also provides the additional advantage of providing the patient with an indication that therapy adjustment may be needed that will further improve her HbA1C level^2,15. The SAP therapy provides the opportunity for this patient to have a more flexible lifestyle especially while traveling. She can see how food, insulin, exercise and other daily activities affect her glucose level – potentially improving overall glucose management.